Diabetes Mellitus or what we often hear the acronym DM is a type of metabolic disease characteristics that would happen hyperglycemia caused by abnormal insulin secretion, insulin action, or both. Clinically there is or is divided into two kinds of diabetes are type 1 diabetes mellitus is Insulin Dependent Diabetes Mellitus (IDDM) and Type 2 Diabetes Mellitus ie Non Insulin Dependent Diabetes Mellitus (NIDDM).
Diabetes mellitus type 1 is a shortage of insulin in the pancreas caused by destruction of the autoimmune by the B cells of the pancreas, is also related to certain HLA on chromosome six and also in some autoimmune serologic as well as cell-mediated, diabetes mellitus who are closely associated with malnutrition and also some other causes that lead to the primary damage beta cells so it is necessary to require insulin from the outside that will serve to survive.
Overview of Diabetes type 2
Viral infections in or near before onset is also often mentioned relationship between the pathogenesis of diabetes. Diabetes type 2 does not have a relationship with the name of HLA, viral or auto immunity. Occurs due to insulin resistance in peripheral tissue insulin production which will be followed by the beta cells of the pancreas are sufficient. Diabetes mellitus type 2 is often also require insulin but not to be dependent on insulin for life.
The diagnosis of diabetes mellitus is strongly based on the examination of blood sugar levels. There is a difference between being in a diagnostic test with Team Diabetes Mellitus screening. Diabetes mellitus diagnostic tests performed on those who would show symptoms and signs of DM, while an examination of the filters aimed at those who no symptoms, which will have the risk of diabetes mellitus.
Examination of the filter needs to be undertaken in the group with one that would be at risk of diabetes as follows:
Age . 45 years.
Weight: BBR> 110% BB dream or BMI> 23 kg / m2.
Hypertension> 140/90 mmHg.
History of diabetes in the lineage.
A history of recurrent miscarriage, giving birth to deformed babies or babies born Weight> 4000 g.
HDL cholesterol <35 mg / dl dserta triglycerides> 250 mg / dl.
The clinical diagnosis of diabetes mellitus generally will be considered if there is a complaint often typical form, polidipsi, polyuria, polyphagia and also a decrease in body weight that can not be described it. Yet Another complaint would probably be presented to the patient is tingling, weakness, itching, blurred eyes as well as erectile dysfunction of men, and also pruritus vulva against female patients. If the complaint is typical, the examination of blood glucose dilakakukan when> 200 mg / dl was sufficient to uphold the diagnostic tests in patients with DM.
For groups that no complaints typical of Diabetes Mellitus, results of examination of new blood glucose levels once abnormal is not strong enough to enforce the inspection of diagnosis of DM. Would But it is necessary assurance that further to receive once again the numbers are abnormal, both fasting blood glucose levels> 126 mg / dl or blood glucose when> 200 mg / dl on another day or also from the results of the tested oral glucose tolerance (OGTT) which were obtained by blood glucose levels after the imposition of> 200 mg / dl.
Tags: Diabetes Mellitus, Health Info, Health
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